Learning Goals by Lecture

2 Lecture 2: Generalized Linear Models: Model Selection and Multinomial Logistic Regression

  • Perform likelihood-based model selection through analysis of deviance, Akaike Information Criterion, and Bayesian Information Criterion.
  • Extend the link function concept of the generalized linear models (GLMs) to other discrete categorical responses.
  • Outline the modelling framework of the Multinomial Logistic regression.
  • Fit and interpret the Multinomial Logistic regression.
  • Use the Multinomial Logistic regression for prediction.

3 Lecture 3: Generalized Linear Models: Ordinal Logistic Regression

  • Outline the modelling framework of the Ordinal Logistic regression.
  • Explain the concept of proportional odds.
  • Fit and interpret Ordinal Logistic regression.
  • Use the Ordinal Logistic regression for prediction.
  • Explain the concept of non-proportional odds.
  • Assess the assumption of proportional odds via the Brant-Wald test.
  • Contrast the Ordinal Logistic regression models under proportional and non-proportional odds assumptions.

4 Lecture 4: Linear Mixed-effects Models

  • Identify the model assumptions in a linear Mixed-effects model.
  • Associate a term (or combination of terms) in a Mixed-effects model with the following quantities:
    • Fixed effect estimates.
    • Variances of the random effects.
    • Regression coefficients for each group and population.
    • Predictions on existing groups and a new group.
  • Fit a linear Mixed-effects model in R, and extract estimates of the above quantities.
  • Identify the consequences of fitting a fixed-effects linear regression model when there are groups, whether a slope parameter is pooled or fit separately per group.
  • Explain the difference between the distributional assumption on the random effects and the fixed effects estimates’ sampling distribution.

5 Lecture 5: Survival Analysis

  • Identify when data is censored.
  • Understand the consequence of subsetting to uncensored data or ignoring the censored property instead of using Survival Analysis methods.
  • Obtain univariate estimates for the mean, median, and survival function in R with a parametric technique.
  • Obtain univariate estimates for the mean, median, and survival function in R with the Kaplan-Meier technique.
  • Identify when the Kaplan-Meier survival function estimate cannot produce mean and high quantile estimates.
  • Outline the modelling framework of a Cox Proportional Hazards model.
  • Fit a Cox Proportional Hazards model in R.
  • Interpret the regression coefficients of a Cox Proportional Hazards model, and identify the model assumptions.
  • Obtain predicted survival functions from a Cox Proportional Hazards model.

6 Lecture 6: Local Regression

  • Define the concept of local regression.
  • Model and perform piecewise constant, linear, and continuous linear local regressions.
  • Extend the concept of \(k\)-NN classification to a regression framework.
  • Define and apply locally weighted scatterplot smoother regression.

7 Lecture 7: Quantile Regression

  • Review what a quantile is.
  • Compare the error functions of Ordinary Least-squares (OLS) regression versus Quantile regression.
  • Recognize the impacts of parametric and distributional assumptions in Quantile regression.
  • Perform non-parametric Quantile regression.
  • Perform parametric Quantile regression.

8 Lecture 8: Missing Data

  • Identify and explain the three common types of missing data mechanisms.
  • Identify a potential consequence of removing missing data on downstream analyses.
  • Identify a potential consequence of a mean imputation method on downstream analyses.
  • Identify the four steps involved with a multiple imputation method for handling missing data.
  • Use the mice package in R to fit multiple imputed models.